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Rarely, a lamia of great divine power undergoes an unholy and dramatic transformation, increasing in size and speed to become a truly intimidating foe. Manipulators and slavers, spiritual leaders and oppressive tyrants, lamia harridans are megalomaniacal, corrupt, and brutal.
The Harridan Template appeared in Appendix Six: Bestiary, page 404 of the Rise of the Runelords Anniversary Edition. It can be placed upon a Large size class lamia or lamia matriarch that has at least 10 levels in a Divine spellcasting class, though the template does not mesh perfectly with the lamia matriarch's abilities.